Using WGCNA (weighted gene co-expression network analysis) to identify the hub genes of skin hair follicle development in fetus stage of Inner Mongolia cashmere goat

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Expression of fox-related genes in the skin follicles of Inner Mongolia cashmere goat

OBJECTIVE This study investigated the expression of genes in cashmere goats at different periods of their fetal development. METHODS Bioinformatics analysis was used to evaluate data obtained by transcriptome sequencing of fetus skin samples collected from Inner Mongolia cashmere goats on days 45, 55, and 65 of fetal age. RESULTS We found that FoxN1, FoxE1, and FoxI3 genes of the Fox gene f...

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Post-Natal Skin Follicle Development in The Raieni Cashmere Goat

One hundred eighty (180) skin samples were taken from the mid-right side of 30 Raieni Cashmere goat male and female kids at 1 mo, 1.5 mo, 2 mo, 2.5 mo, 3 mo and 3.5 mo of age. Numbers of primary and secondary skin follicles were determined for each sample. Numbers of secondary follicles increased until 3 mo of age, but numbers of primary follicles did not change after birth of the kids. The ski...

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Expression of the RORα gene in Inner Mongolian cashmere goat hair follicles.

The expression of retinoid-acid-related orphan receptor α (RORα) was evaluated at the mRNA level using real-time polymerase chain reaction (qRT-PCR), and its expression localization was determined by in situ hybridization of adult Inner Mongolian cashmere goats at different times of the year. In situ hybridization demonstrated that RORαwas expressed in secondary hair follicles of the hair shaft...

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Exploring Differentially Expressed Genes by RNA-Seq in Cashmere Goat (Capra hircus) Skin during Hair Follicle Development and Cycling

Cashmere goat (Capra hircus) hair follicle development and cycling can be divided into three stages: anagen, catagen and telogen. To elucidate the genes involved in hair follicle development and cycling in cashmere goats, transcriptome profiling of skin was carried out by analysing samples from three hair follicle developmental stages using RNA-Seq. The RNA-Seq analysis generated 8487344, 81425...

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ژورنال

عنوان ژورنال: PLOS ONE

سال: 2020

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0243507